The integration of IoT technologies in healthcare is revolutionizing UX design for medical devices, making user-centered design and human factors engineering (HFE) critical for ensuring better patient outcomes and regulatory compliance. With a diverse user base, including patients, caregivers, and medical professionals from various cultural and geographic backgrounds, designers must account for varying capabilities and global usability. Evolving demands, such as telehealth, self-care devices, and less invasive treatments, require intuitive and streamlined interfaces for nonclinical users. UX extends beyond user interfaces, influencing hardware, software, and ecosystems to ensure devices integrate seamlessly into care settings. Early involvement of UX teams in the design process is essential to avoid costly inefficiencies and create intuitive, market-ready devices. Utilizing tools like journey mapping and prototyping, and adhering to HFE-driven UX methodologies, helps secure safe, effective devices with minimal training, while achieving regulatory approval and market success.