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Pigmentation Eyes refers to the presence of colored spots or changes in the iris, sclera, or retina of the eyes due to excess melanin or other pigments. Common causes include genetic factors, aging, and certain medical conditions like Horner's Syndrome or ocular melanoma. Pigmentation changes can manifest as dark spots, altered eye color, or discomfort. While often benign, such changes should be evaluated by an eye care professional to rule out serious issues. Treatments vary based on the cause and may involve observation, medication, or surgical intervention if necessary. Regular eye exams can help manage and monitor these changes effectively.