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Near-Infrared (NIR) Fluorescent Imaging - CD Bioparticles CD Bioparticles offers custom NIR fluorescent imaging contrast agents with ideal optical properties. With years of expertise in diagnosis and imaging contrast agents development, our experienced scientists can construct both organic and inorganic nanoparticles fluorophores for NIR fluorescent imaging. The NIR region (700-1100 nm) falls in the region of the spectrum with the lowest absorption in tissue and therefore enables the deepest tissue penetration. Conventional organic NIR contrast agents suffer from rapid photobleaching, nonspecific adsorption of proteins, and biological degradation. Due to their exceptional fluorescence brightness and stability, inorganic nanoparticles based NIR contrast agents have been extensively investigated. These nanoparticles include semiconductor quantum dots (QDs), gold nanoshells, as well as dye-encapsulating nanoparticles.