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Jaundice itself is a sign of an underlying disease wherein there is an abnormal accumulation of the yellow pigment, bilirubin, in the body. Along with yellow discoloration of conjunctiva and mucosa, there could be other symptoms as well, such as extreme weakness, anorexia, nausea, vomiting, yellow colored urine, pale stools at times, generalized itching, fatigue, headache and malaise.