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Nitrobenzene Market: Global Overview and Forecast (2022-2027) Nitrobenzene is not found in nature. It is an artificial compound that is used to make aniline, the main chemical integrator used in the manufacturing of polyurethanes; nitrobenzene is often used as a solvent in oil refining, as a solvent in the development of cellulose ethers and acetates, as a solvent in the supply of dinitrobenzenes and dichloroanilines, and in the production of organic substances, which include acetaminophen.