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The Science Behind Fat Freezing Basically, there are two ways to use fat freezing treatment. First, there’s the “restore-particular body parts” method which simply freezes off those fat cells that have been damaged or removed by surgery. Second, patients can use “cell selective ultrasonic lipolysis” to target and remove fat from specific, pinpoint locations in the body. This type of fat freezing treatment is considered the safest and most successful among many patients.