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According to the CDC, in the U.S., the leading cause of death for women and men of most ethnic groups is heart disease, and every 36 seconds, one person dies from it. When the supply of oxygen-rich blood to the heart stops or decreases, coronary heart disease develops, which is one of the most-common CVDs and a key factor behind heart attacks. There are many reasons for heart diseases, including age, bad lifestyle choices, genetics, certain infections (such as untreated strep, which can cause rheumatic heart disease), and a few environmental factors, such as toxins. The first step in lowering the incidence of CVDs is to improve diagnostics. With an ever-evolving understanding of the molecular changes linked to CVDs, particularly inherited heart disorders, there is an urgent need to identify effective and sophisticated diagnostic approaches, for minimizing the clinical burden imposed by such diseases. Therefore, healthcare settings are integrating molecular diagnostic tests for the evaluation of CVDs, to provide improved clinical insights and early treatment solutions.