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What Causes Dark Patches in Armpits—and How to Treat Them Naturally Dark patches in armpits often come from daily habits like shaving, friction from tight clothes, or build-up of dead skin cells. These dark spots form when the skin makes more melanin to protect itself. Natural remedies—like aloe vera, turmeric, and apple cider vinegar—help gently lighten skin without harm. If these patches don’t improve or become itchy or painful, it could signal Acanthosis Nigricans, a condition linked to insulin issues—so it's best to consult a dermatologist.