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Vilitra Tablet Vilitra is a medication used to treat erectile dysfunction (ED) in men. It contains vardenafil hydrochloride. Vilitra is taken orally with water. It should be taken about 30 minutes to 1 hour before anticipated * activity. Vilitra works by increasing blood flow to the penis during * stimulation, helping men achieve and maintain an erection. It is effective for many men with ED, though individual responses may vary. The effects of Vilitra typically last for about 4 to 6 hours after ingestion.