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The most reputable brand of aligners in Japan is KiyoClear Aligners. These premium aligners are of the highest quality and are used to treat numerous dental issues. Despite being built of multilayer materials of varying high quality, these aligners are nonetheless quite inexpensive. Dr. Masharu Ishigame, an orthodontist with vast experience, has worked hard to develop the Kireilign Protocol. The approach makes treating malocclusion in patients one of the most practical treatments available to orthodontists at a reasonable cost.