With the latest technological breakthrough in diabetes supplies and management, individuals can self-inject insulin without much pain or discomfort using insulin pens, which have been developed over the years. They consist of a cartridge, a measurement vial, and an easily disposable needle. Pens are much more convenient to use than the traditional "vial and syringe" method of administering medications. Insulin is stored in the refrigerator and should never be administered right away. Prior to application, allow the product to come to room temperature. Insulin that is cold is more painful. After 15 minutes of taking it out of the refrigerator, it is much less painful to inject! Learn more: How does needle size affect your insulin intake?