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The heart valve replacement cost in India ranges between Rs. 2.5 lakhs to Rs. 3 lakhs approximately depending on the procedure used. Heart valve surgery is recommended to treat various kinds of heart valve diseases. The surgical procedure is generally the last option when other treatment options have failed or if the condition progresses rapidly. The heart valve replacement cost in India ranges between Rs. 2.5 lakhs to Rs. 3 lakhs approximately depending on the procedure used.