Catecholamine-Sensitive Pleomorphic Ventricular Tachycardia | Creative Bioarray
Catecholamine-sensitive pleomorphic ventricular tachycardia (CPVT) is a primary cardiac electrical disorder that occurs mostly in adolescents with no organic heart disease and a normal QT interval. Characterized by bidirectional or polymorphic ventricular tachycardia (VT) during exercise or emotional agitation, leading to syncope and sudden death. The disease was first reported by Reid et al. in 1975. Since then, there have been multiple cases reported, but the diagnosis name is different. In 1995, Leenhardt et al. reported the first larger series of case studies, describing in detail the clinical manifestations of the disease, and officially named the disease with this clinical feature CPVT. Subsequently, more and more people realized that CPVT is an important cause of sudden death in patients with non-organic heart disease, and they have also updated their etiology, pathogenesis, and diagnosis and treatment strategies.