Afobazole (Fabomotizole) 60 Tablets x 10 mg

Fabomotizole (Afobazole) is an anxiolytic pill launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms.
Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have shown antimutagenic and antiteratogenic properties.

Fabomotizole is used to treat the following symptoms:

- Generalized symptoms of anxiety disorder
- Alcohol and nicotine withdrawal
- Tensions in the body
- Various somatic disorders
- Irritability
- Sleep disorders caused by anxiety

Country of Manufacture: Russian Federation